Toxic metals such as arsenic, cadmium, lead, and mercury are ubiquitous, have no beneficial role in human homeostasis, and contribute to noncommunicable chronic diseases. While novel drug targets for chronic disease are eagerly sought, potentially helpful agents that aid in detoxification of toxic elements, chelators, have largely been restricted to overt acute poisoning. Chelation, that is multiple coordination bonds between organic molecules and metals, is very common in the body and at the heart of enzymes with a metal cofactor such as copper or zinc. Peptides glutathione and metallothionein chelate both essential and toxic elements as they are sequestered, transported, and excreted. Enhancing natural chelation detoxification pathways, a...
Chelation therapy is a consolidated medical procedure used primarily to reduce the toxic effects of ...
Oxidative stress contributes to the pathophysiology of exposure to heavy metals/metalloid. Beneficia...
Heavy metals, which have widespread environmental distribution and originate from natural and anthro...
Toxic metals such as arsenic, cadmium, lead, and mercury are ubiquitous, have no beneficial role in ...
Background: Exposure to heavy metals leads to functional and metabolic disturbances and many of the...
Metal ions poisoning can result from environmental factors, intentional action, or disruption of hom...
The use of chelating agents to remove toxic metal ions in different human pathologies has been large...
Purpose of Review Chelation therapy is used for diseases causing an imbalance of iron levels (for ex...
Heavy metal toxicity has been known for thousands of years, but efforts are still underway to remedi...
Chelation therapy is a consolidated medical procedure used primarily to reduce the toxic effects of ...
Metal intoxication, thus is an important concern in the world today owing to high industrial and che...
Chelation therapy plays a prominent role in the clinical treatment of metal intoxication. In this pa...
It will soon be twenty years since the last chelating agent was clinically approved to be used again...
In this paper we took into examination the use of chelation therapy for treating metal intoxication ...
Metal ions are required for many critical functions in humans. Scarcity of some metal ions can lead ...
Chelation therapy is a consolidated medical procedure used primarily to reduce the toxic effects of ...
Oxidative stress contributes to the pathophysiology of exposure to heavy metals/metalloid. Beneficia...
Heavy metals, which have widespread environmental distribution and originate from natural and anthro...
Toxic metals such as arsenic, cadmium, lead, and mercury are ubiquitous, have no beneficial role in ...
Background: Exposure to heavy metals leads to functional and metabolic disturbances and many of the...
Metal ions poisoning can result from environmental factors, intentional action, or disruption of hom...
The use of chelating agents to remove toxic metal ions in different human pathologies has been large...
Purpose of Review Chelation therapy is used for diseases causing an imbalance of iron levels (for ex...
Heavy metal toxicity has been known for thousands of years, but efforts are still underway to remedi...
Chelation therapy is a consolidated medical procedure used primarily to reduce the toxic effects of ...
Metal intoxication, thus is an important concern in the world today owing to high industrial and che...
Chelation therapy plays a prominent role in the clinical treatment of metal intoxication. In this pa...
It will soon be twenty years since the last chelating agent was clinically approved to be used again...
In this paper we took into examination the use of chelation therapy for treating metal intoxication ...
Metal ions are required for many critical functions in humans. Scarcity of some metal ions can lead ...
Chelation therapy is a consolidated medical procedure used primarily to reduce the toxic effects of ...
Oxidative stress contributes to the pathophysiology of exposure to heavy metals/metalloid. Beneficia...
Heavy metals, which have widespread environmental distribution and originate from natural and anthro...